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It’s a fact. Approximately 25% of individuals taking ASA to prevent cardiovascular events are resistant to the beneficial effect of ASA (such as Aspirin* or Entrophen*).

If you are ASA resistant, taking ASA daily will have no affect whatsoever on your risk for heart attack or stroke.

The good news is that ASA Effect™ is easy to test, and there are steps doctors can take to help patients when ASA is not working.

ASA Effect is the only Health Canada-cleared test that helps doctors accurately determine a patient’s response to ASA by measuring the urine levels of a metabolite of thromboxane, the target of ASA therapy.

To learn more about taking ASA to reduce the risk of heart attack and stroke, the Food and Drug Administration published these consumer tips.

ASA (such as Aspirin*) is frequently called a "wonder drug" because of its many beneficial properties. One of the most amazing effects of ASA is that it makes blood platelets less sticky, which can prevent blood clots from forming. If blood clots cannot form within the arteries, blood flows more freely, and the risk of heart attack and stroke is reduced.

It is estimated that over 4 million people in Canada take ASA every day to help prevent heart attacks and strokes. However, research has demonstrated that up to 25 percent of these individuals may not benefit from the anti-clotting effect of ASA, and are more than three times more likely to die from a heart attack or stroke.

ASA does not have the same effect on everyone. The suboptimal response to ASA by an individual is commonly known as “ASA resistance”. Since these individuals are at increased risk of heart attack or stroke, doctors are beginning to recognize the importance of testing for ASA effect.

Until recently, there was no quick, accurate and effective way to be tested for ASA effect. Now, with the Health Canada-cleared ASA Effect test, you and your doctor can be sure your ASA is working with a simple urine test. The ASA Effect test sample collection can be done at a Patient Specimen collection centre or at your physician’s office.


Research: Aspirin* Resistance may lead to sub-optimal dosing in people with Diabetes

Original Research: “Aspirin* Use Rates in Diabetes: A Systematic Review and Cross-Sectional Study” A study in the Canadian Journal of Diabetes (2010;34(3):211-217) has concluded “…our study identified that about one-quarter of people with diabetes who have an indication for primary prevention and over 70% of those with a history of CV events use aspirin regularly. The most common [...]

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ASA is the abbreviation for Acetylsalicylic Acid
*In Canada, Aspirin is a trademark of Bayer AG, used under license.
*Entrophen is a Registered trademark of PendoPharm.
*ASA Effect and its logo are trademarks of Bescot Healthcare Canada Inc.